利培酮对脑电图影响的研究

目的：研究利培酮引起脑电图改变的特征，其改变与用药时间、剂量及疗效之间关系，并与氯氮平引起的脑电图异常作一比较。方法：符合ＣＣＭＤ－２－Ｒ诊断的精神分裂症、分裂样精神病患者入组。在服药前、服药后１周、２周４周分别检查脑电图，产淫药剂量，测定简明精神病评定量表（ＢＰＲＳ）观察疗效。结果：服用利培酮后脑电图波率变慢，服用１周后即出现脑电图异常（Ｐ〈０．０１），与剂是琢疗效无关，异常率及异常程度轻于氯氮

Electroencephalogram (EEG) in patients treated by risperidone

Objective:To study EEG features of patients treated by risperidome and the relationship between EEG and the period of administration,dosage and clinical response.The comparison group took in clozapine. Method:EEG,risperidone dosage,efficacy (BPRS scores) were recorded in patients with diagnosis of schizophrenia,schizophreniform psychosis according to CCMD 2 R before and after using risperidone. Results:The basic electric activities of EEG became slow after using risperidone.There were no association between dosage and clinical response. Conclusion:The abnomal EEG was lesser serious in risperidone than clozapine.