Angina without involvement of large coronary trunks and precapillary pulmonary hypertension in a patient with periarteritis nodosa |
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| Authors: | P Marette B Molle J L Mas A Kahan J Y Devaux M Toussaint P Volkringer J Fouchard |
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| Affiliation: | Service des Maladies Cardiovasculaires, H?pital Cochin, Paris. |
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| Abstract: | A patient affected with periarteritis nodosa and angina, presented a normal coronary angiography of the coronary trunks and an alteration of the left ventricular systolic function, improved by nicardipine, as well as a pre-capillary pulmonary hypertension with isolated, right cardiac repercussions, without pulmonary fibrosis nor thromboembolic disease. In addition, he presented three transient cerebral ischaemic accidents, with different localizations, which could not be related to a right aneurysm of the sylvian artery. Isolated precapillary pulmonary hypertension, without pulmonary fibrosis, which is not described in the course of periarteritis nodosa, seems related to an arteriolar involvement which is the known substratum of other visceral involvement in periarteritis nodosa. Improvement of the left ventricular function with nicardipine, administered acutely, suggest a partially reversible disorder of the coronary microcirculation. |
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