Quantitation in gated perfusion SPECT imaging: The Cedars-Sinai approach |
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Authors: | Guido Germano Paul B Kavanagh Piotr J Slomka Serge D Van Kriekinge Geoff Pollard Daniel S Berman |
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Institution: | (1) Department of Medicine, Cedars-Sinai Medical Center, 8700 Beverly Blyd. Ste. A047, 90048 Los Angeles, Calif.;(2) Department of Imaging, Cedars-Sinai Medical Center, 8700 Beverly Blyd. Ste. A047, 90048 Los Angeles, Calif.;(3) Department of Medicine, David Geffen School of Medicine at UCLA, Los Angeles, Calif. |
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Abstract: | Cedars-Sinai’s approach to the automation of gated perfusion single photon emission computed tomography (SPECT) imaging is
based on the identification of key procedural steps (processing, quantitation, reporting), each of which is then implemented,
in completely automated fashion, by use of mathematic algorithms and logical rules combined into expert systems. Our current
suite of software applications has been designed to be platform- and operating system-independent, and every algorithm is
based on the same 3-dimensional sampling scheme for the myocardium. The widespread acceptance of quantitative software by
the nuclear cardiology community (QGS alone is used at over 20,000 locations) has provided the opportunity for extensive validation
of quantitative measurements of myocardial perfusion and function, in our opinion, helping to make nuclear cardiology the
most accurate and reproducible modality available for the assessment of the human heart. |
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