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Multimarker panel in patients admitted to emergency department: a comparison with reference methods |
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| Authors: | Gruson Damien Thys Frédéric Ketelslegers Jean Marie Pasquet Agnes Delvau Nicolas Deneys Véronique Verschuren Franck |
| Affiliation: | a Department of Endocrinology and Nutrition, Unit of Diabetes and Nutrition, Cliniques Universitaires St-Luc, Brussels, Belgium b Department of Cardio-vascular Medicine, Cardiology Service, Cliniques Universitaires St-Luc, Brussels, Belgium c Department of Acute Medicine, Emergency Unit, Cliniques Universitaires St-Luc, Brussels, Belgium d Department of Clinical Biology, Laboratory of Haemostasis, Cliniques Universitaires St-Luc, Brussels, Belgium |
| Abstract: | ObjectivesPoint of care testing and multimarker panels are rapidly expanding in emergency departments. We determined the reliability of Short-of-Breath SOB® panel in patients admitted for acute dyspnea and/or chest pain.Design and methodsSOB® d-dimer, BNP, cTnI, CK-MB and myoglobin assays were compared with references in 97 outpatients.ResultsThe correlation between SOB® and references methods was acceptable, but with limited precision and accuracy.ConclusionsDiagnostic performances and cut-off values should be further validated before clinicians replace traditional cardio-respiratory biomarkers by the new SOB® panel. |
| Keywords: | Multimarker BNP Troponin Dyspnea Chest pain Emergency triage |
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