14例老年多原发肺癌临床分析

目的：研究老年肺多原发癌的临床诊断、治疗和预后。方法：回顾性分析281例经病理证实的老年肺癌患者，对其中14例肺多原发癌进行临床分析。结果：本组老年肺多原发癌14例占4．98％（14／281），其中双原发癌13例（92．9％），三原发癌1例（7．1％）。首癌平均生存期114．3月，首癌与重癌间隔平均52．2月。11例重癌接受治疗后平均生存47．2月，手术治疗者6例平均生存71．2月，显著长于非手术治疗者的18．4月。结论：随存活时间的延长，重复癌的发生的危险逐渐增加，尤其是存活2年以上，因此需要对肺原发癌治疗后存活的患者长期终生追踪。为获得较好的预后，对重复癌要尽可能推荐手术治疗。

A clinical analyses on multiple primary lung cancers in 14 elderly patients

Objective:To study the diagnosis, treatment and prognosis of multiple primary lung cancers (MPLC) in elderly patients Methods: 14patients with MPLC from 281 patients of lung cancer confirmed by pathology and cytology were retrospectively reviewed and analyzed clinically Results: The incidence of the MPLC comprised of 4 98%(14/281); 13 patients had double primary cancers, 1 patients had three primary cancers; the mean survival of the first cancer was 114 3 months; the mean interval between primary tumor and the second tumor was 52 2 months; 6 patients with MPLC underwent resection of tumor, their mean survival was 71 2 month, which was longer than that of 5 patients without surgical treatment18 4 months Conclusions: The surviving patients of primary lung cancers require lifelong screening for MPLC, because the incidence of the MPLC are increasing in long surviving patients, the surgical treatment should be recommended