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First description of blaNDM-1, blaOXA-48, blaOXA-181 producing Enterobacteriaceae strains in Romania
Authors:Edit Szé  kely,Ivelina Damjanova,Laura Já  nvá  ri,Krisztina E. Vas,Szabolcs Molná  r,Doina V. Bilca,Lilla K. Lőrinczi,Á  kos Tó  th
Affiliation:1. University of Medicine and Pharmacy, Targu Mures, Romania;2. Mures County Clinical Emergency Hospital, Targu Mures, Romania;3. National Center for Epidemiology, Budapest, Hungary
Abstract:We report the first isolation and characterization of several Enterobacteriaceae strains harboring blaNDM-1, blaOXA-48 and/or blaOXA-181 genes in a Romanian emergency teaching hospital. Between January 2010 and September 2012 nine carbapenemase-producing Enterobacteriaceae strains were identified. The blaNDM-1 gene was present in two Enterobacter cloacae strains, an Escherichia coli and two Klebsiella pneumoniae strains. One of these K. pneumoniae strains also harbored the blaOXA-181 gene. Three other K. pneumoniae strains and one Serratia marcescens carried blaOXA-48.
Keywords:Antimicrobial resistance   Carbapenemases   NDM-1   OXA-48   Molecular characterization
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