降钙素原对细菌性脓毒症早期诊断的临床意义

目的探讨降钙素原（procalcitonin，PCT）在细菌性脓毒症患者中的应用价值。方法回顾分析了15例细菌性脓毒症患儿和21例非脓毒症患儿的临床资料，对各自血清降钙素原与C反应蛋白（C—reactive protein，CRP）以及血常规白细胞、中性粒细胞比例等传统炎性指标进行了比较分析。结果细菌性脓毒症组的PCT阳性率及PCT≥2ng／ml例数比例均明显高于非脓毒症组（P〈0．01）传统炎症指标均显示细菌性脓毒症组与非脓毒症组比较，差异无统计学意义（P〉0．05）。结论PCT检测可以作为早期诊断细菌感染所致脓毒症的可靠依据。

Clinical value of procalcitonin for the early diagnosis of bacterial sepsis

Objective To evaluate the value of procalcitonin （PCT） for bacterial sepsis in children. Methods Retrospective analysis was carried out on the clinical data of 15 cases with bacterial sepsis and 21 cases with non - sepsis on their respective serum PCT,and other traditional inflammatory indicators of CRP and white blood cell （WBC） , neutrophil ratio （N）, and comparative analysis was made. Results Levels of PCT in bacterial sepsis group were significantly higher than those in non - sepsis group （ P 〈 0.01 ） ,the number ratio of the cases with PCT ≥ 2ng/ml was significantly ihigher too, but no differences were found among CRP, WBC, N （P 〉 0.05 ）. Conclusions PCT can be used as reliable basis for the early diagnosis of bacterial sepsis.