| 急性冠状动脉综合征患者血清高敏C反应蛋白和新蝶呤的检测及意义 |
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| 引用本文： | 程致,谭明灯,张德权.急性冠状动脉综合征患者血清高敏C反应蛋白和新蝶呤的检测及意义[J].中国基层医药,2006,13(2):235-236. |
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| 作者姓名： | 程致 谭明灯 张德权 |
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| 作者单位： | 1. 404000,重庆市,重庆三峡中心医院百安分院心内科
2. 山东大学齐鲁医院心内科 |
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| 摘 要： | 目的研究急性冠状动脉综合征（ACS）患者血清中炎症反应标记物高敏C反应蛋白（HS-CRP）和免疫反应标记物新蝶呤的变化。方法同时选取ACS患者和慢性稳定型心绞痛（SAP）患者各80例，采用酶联免疫法测定上述患者血中HS-CRP、新蝶呤浓度。结果与SAP患者相比，HS-CRP、新蝶呤的浓度在ACS患者血清中显著增高（均P〈0．05）。结论HS-CRP和新蝶呤可以作为诊断和预测ACS发生的敏感指标，炎症反应和免疫反应均参与了ACS的发生。
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| 关 键 词： | 冠状动脉疾病 C反应蛋白 新蝶呤 急性冠状动脉综合征 检测 |
| 收稿时间： | 2005-04-25 |
| 修稿时间： | 2005年4月25日 |
Serum levels of chemoattractants high-sensitivity C-reactive protein and neopterin with acute coronary syndrome and their clinical significance |
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| CHENG Zhi,TAN Ming-ding,ZHANG De-quan.Serum levels of chemoattractants high-sensitivity C-reactive protein and neopterin with acute coronary syndrome and their clinical significance[J].Chinese Journal of Primary Medicine and Pharmacy,2006,13(2):235-236. |
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| Authors: | CHENG Zhi TAN Ming-ding ZHANG De-quan |
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| Institution: | Departrneng of Cardiology, Chongqing Three Gorges Central Hospital Baian Fenyuan , Wanzhou , Chongqing , 404000, China |
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| Abstract: | Objective To investigate the change of the inflammatory marker high-sensitivity C-reactive protein(HS-CRP) and the immune marker neopterin in patients with acute coronary syndrome(ACS).Methods The study population included 40 patients with acute myocardial infarction(AMI) and 40 patients with unstable angia pectons(UAP).At the same time,we selected 80 patients with chronic stable angia pectons.Serum levels of HS-CRP,neopterin were measured by means of ELISA.Results HS-CRP and neopterin were significantly higher in acute coronary syndrome group than those in chronic stable angina group.Conclusion HS-CRP and Neopterin are elevated in acute coronary syndrome.They can be used as the certain diagnosetic value for ACS.This study also supports the hypothesis that both immune and inflammation play roles in ACS. |
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| Keywords: | Coronary artery disease C-reactive protein Neopterin |
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