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Radial maze learning in two inbred mouse strains and their reciprocal congenics for the non-pseudoautosomal region of the Y chromosome
Authors:Frans Sluyter   Charlotte C. M. Marican   Pierre L. Roubertoux  W. E. Crusio
Affiliation:Department of Psychoneuropharmacology, Geert Grooteplein N 21, P.O. Box 9101, 6500 HB, Nijmegen, The Netherlands. f.sluyter@pmf.kun.nl
Abstract:The effect of the non-pseudoautosomal region of the Y chromosome on spatial learning in a radial maze task was examined in two inbred mouse strains, NZB and CBA/H, and their respective congenics for the Y(NPAR). Seven variables reflecting learning performance, learning strategy and lateralisation were measured. We found no substantial effect of the Y(NPAR) on radial maze learning, but modest influences on behavioral strategies. These findings are in agreement with previous results regarding the sizes of the intra- and infrapyramidal mossy fiber (IIPMF) terminal fields.
Keywords:Radial maze learning   Y chromosome   Hippocampus   Mossy fiber   Mouse
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