| 结核分枝杆菌耐药机制和治疗的最新研究进展 |
| |
| 引用本文： | 丁磊,徐俊驰,邱文娜,李晋,胥萍. 结核分枝杆菌耐药机制和治疗的最新研究进展[J]. 现代检验医学杂志, 2021, 0(2): 1-5. DOI: doi:10.3969/j.issn.1671-7414.2021.02.001 |
| |
| 作者姓名： | 丁磊 徐俊驰 邱文娜 李晋 胥萍 |
| |
| 作者单位： | （1.苏州市吴江区儿童医院/苏州大学附属儿童医院吴江院区检验科, 江苏苏州 215200; 2.苏州大学附属传染病医院/苏州市结核病防治重点实验室，江苏苏州 215007） |
| |
| 基金项目： | 江苏省科技项目基础研究计划(BK20161230);苏州市民生科技-关键技术应用研究(SS201879)。 |
| |
| 摘 要： | 结核病（tuberculosis,TB）是由结核分枝杆菌（Mycobacterium tuberculosis, MTB）引起的慢性传染病。近年来，结核分枝杆菌的耐药性变异尤为突出，耐药结核病已成为一个不可忽视的全球公共卫生问题。一直以来，国内外诸多研究聚焦于耐药结核发病机制及治疗方法的研究，并且不断形成新的机制理论和治疗方案。该文着重于对MTB耐药机制及治疗的最新进展进行综述，从而为耐药结核的新药研制及制定更合理的治疗方案提供参考。
|
| 关 键 词： | 结核分枝杆菌 耐药机制 靶点 |
Latest Research Progress on the Drug Resistance Mechanism and Treatment of Mycobacterium Tuberculosis |
| |
| DING Lei,XU Jun-chi,QIU Wen-na,LI Jin,XU Ping. Latest Research Progress on the Drug Resistance Mechanism and Treatment of Mycobacterium Tuberculosis[J]. Journal of Modern Laboratory Medicine, 2021, 0(2): 1-5. DOI: doi:10.3969/j.issn.1671-7414.2021.02.001 |
| |
| Authors: | DING Lei XU Jun-chi QIU Wen-na LI Jin XU Ping |
| |
| Affiliation: | (1.Department of Clinical Laboratory,Children’s Hospital of Wujiang District/Wujiang Branch of Children’s Hospital Affiliated to Suzhou University ,Jiangsu Suzhou 215200，China;2.Infectious Disease Hospital of Suzhou University/Suzhou Key Laboratory of Tuberculosis Prevention and Treatment, Jiangsu Suzhou 215007，China) |
| |
| Abstract: | Tuberculosis(TB)is a chronic infectious disease caused by Mycobacterium tuberculosis(MTB).In recent years,the drug-resistant mutation of Mycobacterium tuberculosis has become particularly prominent,and drug-resistant tuberculosis has become a global public health problem that cannot be ignored.For a long time,many domestic and foreign studies have focused on the pathogenesis and treatment of drug-resistant tuberculosis,and new mechanism theories and treatment plans have been continuously formed.This article focuses on reviewing the latest developments in the mechanism and treatment of MTB resistance,so as to provide references for the development of new drugs and the formulation of more reasonable treatment plans for drug-resistant TB. |
| |
| Keywords: | Mycobacterium tuberculosis drug resistance mechanism target |
| 本文献已被 维普 等数据库收录！ |
| 点击此处可从《现代检验医学杂志》浏览原始摘要信息 |
|
点击此处可从《现代检验医学杂志》下载免费的PDF全文 |
