|
|||||
|
|
Use of bone marrow derived stem cells in a fracture non-union |
|
| Authors: | Binod C. Raulo Chidananda Dash Shakti Rath Sukumar Chakrabarty Padmanav Rautray Jagannath Sahoo Rabindra N. Padhy |
| Affiliation: | 1. Department of Orthopedics, IMS & Sum Hospital, Siksha ‘O’ Anusandhan University, Bhubaneswar, India;2. Central Research Laboratory, IMS & Sum Hospital, Siksha ‘O’ Anusandhan University, Bhubaneswar, India;3. Department of Microbiology, IMS & Sum Hospital, Siksha ‘O’ Anusandhan University, Bhubaneswar, India;4. Department of Pathology, IMS & Sum Hospital, Siksha ‘O’ Anusandhan University, Bhubaneswar, India;5. APE Division, Central Institute of Freshwater Aquaculture, Bhubaneswar, India |
| Abstract: | This is an attempt of using in vitro cultured mesenchymal stem cells (MSCs) from bone marrow in joining of a fracture non-union. Bone marrow cells were obtained and differentially centrifuged for MSCs that were grown in vitro in mesenchymal stem cell basal medium aseptically, for 10 d. The cell mass was injected around the fracture non-union. Healthy conditions of development of tissue regeneration at the trauma site and due bone joining were recorded. It is concluded that in vitro cultured MSCs had a blithesome effect on the fracture non-union. |
| Keywords: | Non-union fracture Autologous bone-marrow cells Mesenchymal stem cells |
| 本文献已被 ScienceDirect 等数据库收录！ | |