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Phytochemical screening and evaluation of anti-inflammatory activity of methanolic extract of Abroma augusta Linn
Authors:Sutapa Das  Rana Datta  Subhangkar Nandy
Affiliation:1. Research unit of Macromolecular Biochemistry and Genetic, Faculty of Sciences of Gafsa, 2112, Gafsa, Tunisie;2. Laboratory Animal Eco Physiology, Faculty of Sciences of Gafsa, Sidi Ahmed Zarrouk, 2112, Gafsa, Tunisie;3. Laboratory of Environmental Physiopathology, Valorization of Bioactive Molecules and Mathematical Modeling, Faculty of Sciences Sfax, Road Soukra km 3.5, PB no 1171-3000, Sfax, Tunisie;1. College of Mongolian Medicine, Inner Mongolia University for Nationalities, Tongliao, 028000, China;2. Inner Mongolia Research Institute of Traditional Mongolian Medicine Engineering Technology, Tongliao, 028000, China;3. Department of Applied Biological Chemistry, The University of Tokyo, 1-1-1 Yayoi, Bunkyo-ku, Tokyo, 113-8657, Japan;1. Department of Molecular and Cellular Engineering, Jacob Institute of Biotechnology and Bioengineering, Sam Higginbottom University of Agriculture, Technology and Sciences, Prayagraj, Uttar Pradesh, 211007, India;2. Department of Life Sciences, Presidency University, 86/1 College Street, Kolkata-700073, West Bengal, India;3. Department of Botany, Deen Dayal Upadhyay Gorakhpur University, Gorakhpur, Uttar Pradesh, 273009, India;4. Institute of Molecular Plant Sciences, School of Biological Sciences, Edinburgh University, King''s Buildings, Mayfield Road, Edinburgh EH9 3JR, United Kingdom;5. Green Bioactives, Roslin Innovation Centre, University of Edinburgh, Easter Bush Campus, Midlothian, EH25 9RG, United Kingdom;6. Department of Plant Biology, Institute of Environmental Biology, Wroc?aw University of Environmental and Life Sciences, Ko?uchowska 5b, 51-631 Wroc?aw, Poland;1. Genoine Research Laboratory Pvt. Ltd., Subhash Nagar, Karimganj, Assam 788710, India;2. Department of Environmental Science, Arunachal University of Studies, Namsai 792103, Arunachal Pradesh, India;3. Department of Botany, Birjhora Mahavidyalaya, Bongaigaon 783380, Assam, India;1. Faculty of Pharmacy, Department of Pharmacognosy, Ain Shams University, 11566 Abbassia, Cairo, Egypt;2. Department of Pharmaceutical Biology, Faculty of Pharmacy and Biotechnology, German University in Cairo, Cairo 11432, Egypt;3. Medical Laboratory Sciences Department, Fakeeh College for Medical Sciences, Jeddah, Saudi Arabia;4. Biochemistry Department, Faculty of Pharmacy, Al-Azhar University, Cairo, Egypt
Abstract:ObjectiveTo evaluate the Phytochemical and anti-inflammatory property of the different parts of methanolic extracts of Abroma augusta Linn.Materials and methodsAbroma augusta Linn (Family-Malvaceae) commonly known as Ulatkambal in Hindi and Devil's cotton in English, found in tropical Asia, South and eastern Africa, and Australia. It is mainly used for dysmenorrhoea, ammenorrhoea, sterlilty and other menstrual disorder. The present study aimed at evaluation of Phytochemical and anti-inflammatory study of different parts of Abroma augusta Linn methanolic extract by the carrageenan induced rat paw oedema method.ResultsThe result showed significant anti-inflammatory property of different parts of Abroma augusta Linn methanolic extract.ConclusionsThe methanolic extract of different parts of Abroma augusta Linn showed potent activity comparing with the standard drug diclofenac sodium perhaps due to the alkaloids and flavonoids present in the plant.
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