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Design,synthesis, and biological evaluation of novel 5‐Alkyl‐6‐Adamantylmethylpyrimidin‐4(3H)‐ones as HIV‐1 non‐nucleoside reverse‐transcriptase inhibitors
Authors:Wenxin Li  Boshi Huang  Dongwei Kang  Erik De Clercq  Dirk Daelemans  Christophe Pannecouque  Peng Zhan  Xinyong Liu
Affiliation:1. Department of Medicinal Chemistry, Key Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Shandong University, Ji'nan, Shandong, China;2. Rega Institute for Medical Research, KU Leuven, Leuven, Belgium
Abstract:
Keywords:anti‐HIV‐1 activity  drug design  HIV‐1  NNRTIs  S‐DABOs
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