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注射用盐酸环丙沙星细菌内毒素检查法建立及方法学研究
引用本文:曾晓红,邓慧英.注射用盐酸环丙沙星细菌内毒素检查法建立及方法学研究[J].海峡药学,2009,21(12):85-86.
作者姓名:曾晓红  邓慧英
作者单位:福建省莆田学院附属医院,莆田,351100
摘    要:目的建立注射用盐酸环丙沙星细菌内毒素检查法。方法参照中国药典2005年版二部附录XIE细菌内毒素检查法进行实验〔1〕。结果当注射用盐酸环丙沙星配制至0.125mg.mL-1浓度时进行细菌内毒素检查无干扰作用。结论注射用盐酸环丙沙星建立细菌内毒素检查法是可行的。

关 键 词:注射用盐酸环丙沙星  细菌内毒素  干扰试验

Study on bacterial endotoxin test establishment and methodology of ciprofloxacin hydrochloride for Injection
ZEN Xiao-hong,DENG Hui-ying.Study on bacterial endotoxin test establishment and methodology of ciprofloxacin hydrochloride for Injection[J].Strait Pharmaceutical Journal,2009,21(12):85-86.
Authors:ZEN Xiao-hong  DENG Hui-ying
Institution:(Attached Hospital of Fujian Putian College Putian 351100, China)
Abstract:OBJECTIVE To establish a method for testing bacterial endotoxin of Ciprofloxacin Hydrochloride for Injection.METHODS According to the Bacterial Endotoxin Test approved by the appendix XIE of Chinese Pharmacopoeia 2005 edition vol Ⅱ.RESULTS Ciprofloxacin Hydrochloride for Injection did not interfere with bacterial endotoxin test when it was diluted to the concentration of 0.125mg·mL-1.CONCLUSION It is suitable for bacterial endotoxin test of Ciprofloxacin Hydrochloride for Injection.
Keywords:Ciprofloxacin Hydrochloride for Injection  Bacterial Endotoxin  Interfere factors test
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