腹水糖抗原检测对恶性腹水的诊断价值

对７９例腹水患者按结核性、非结核良性及恶性分为３组，同步检测腹水ＣＡ５０及ＣＥＡ，结果恶性腹水中ＣＡ５０、ＣＥＡ明显高于另两组，ＣＡ５０诊断恶性腹水的敏感性和特异性分别为７７．８％和９５％，且不受结核等渗出性腹水的影响、作为单项标记，其敏感性优于ＣＥＡ，若二者联合检测敏感性可进一步提高。

EVALUATION OF CA_(50),CEA IN THE DIFFERENTIATION BETWEEN MALIGANT AND NON-MALIGNANT ASCITIC FLUID

To investigate the differential diagnosis of ascites,the authors measured the concentrations of CA(50) and CEA in ascitic fluid of 79 patients simultaneously.The result showed that the level of both CA(50) and CEA in malignant ascites were significantly higher than that in tuberculous ascites and non-tuberculous benign ascites,P<0.01;as a single marker,the sensitivity and specifcity of ascitic CA(50) in the diagnosis of malignant ascites were 77.8%and 93%respectively,but the both of CEA were 52.8%and 93%respectively; Combined measurement of the both could improve the sensitivity significantly,with a little reduction of specificity. The study indicated that ascitic CA(50) and CEA were valuable markers,the evaluation of which was not affected by tuberculous ascited in the diagnosis of malignant ascites;CA(50) was a better marker than CEA in the diagnosis of malignant ascites;And combined measurement of the both could improve the sensitivity singnificantly.