Clearance of passively transferred IgE antibody from peripheral blood of mast cell-deficient W/Wv mice

The plasma decay curve of intravenously injected murine monoclonal or conventional anti-DNP IgE antibody was determined in mast cell-deficient W/Wv and their normal littermate +/+ mice. The results show that the clearance of passively transferred IgE was not altered by mast cell deficiency. Possible sites of clearance and/or catabolism of IgE are discussed.