| 甘草、芍药合剂对离体兔肠管运动的影响 |
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| 引用本文： | 赵玉珍,马春力,郭忠兴,粟坤,谭宏,张学军,潘锡勤. 甘草、芍药合剂对离体兔肠管运动的影响[J]. 黑龙江医药科学, 1992, 0(6) |
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| 作者姓名： | 赵玉珍 马春力 郭忠兴 粟坤 谭宏 张学军 潘锡勤 |
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| 作者单位： | 佳木斯医学院基础药理教研室，佳木斯医学院基础药理教研室，佳木斯医学院基础药理教研室，佳木斯医学院基础药理教研室，佳木斯医学院基础药理教研室，佳市卫生中专，佳市卫生中专 |
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| 摘 要： | 甘草、芍药水提合剂(GPM0.415g)对离体兔肠管运动呈明显抑制作用。降频率作用较降幅度作用为强。给药后5min,降低肠蠕动频率为正常对照组的60.88％与阿托品(0.25mg)对照组比较、降频率作用明显,且维持时间较长。给药后5～10min,降幅度作用两者相接近,给药后15min,幅度降低是阿托品组的1.15倍,但无显著性差异(P>0.05);给药后20min,降幅度作用则为阿托品的1.85倍,两者比较有显著性差异(P<0.01)。GPM亦能够拮抗氯化钡(BaCl_2),乙酰胆碱(Ach)、组织胺对离体兔肠平滑肌的兴奋作用。
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| 关 键 词： | 甘草 芍药 平滑肌 兔 |
Effects of Glycyrrhiza-Paeonia mixture on intestinal smooth muscle in isolated rabbits |
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| Zhao Yuzhen. Effects of Glycyrrhiza-Paeonia mixture on intestinal smooth muscle in isolated rabbits[J]. Heilongjiang Medicine and Pharmacy, 1992, 0(6) |
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| Authors: | Zhao Yuzhen |
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| Affiliation: | Zhao Yuzhen |
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| Abstract: | Glycyrrhizia -- Paeonia mixture (GPM0. 415g) could inhibit movement of intestinal smooth muscle in isolated rabbits significantly Frequency--reducing effect was stronger than amplitude -- decreasing effect. 5 minutes after administration, frequency -- decreasing effect was 66. 88% of normal control group and more apparent, keeping longer, compared with Atropine control group (0. 25mg), 5 and 10 minutes after administration amplitude - decreasing effect was similar in both groups, 15 minutes after administration, amplitude - decreasingeffect was 1. 15 times as much as that of Atropine group with no significant difference (P>0. 05) and 20 minutes after that, 1. 85 times as much as that of Atropine group with significant difference (P<0. 01). |
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| Keywords: | Glycyrrhizia Paeonia smooth muscle rabbit |
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