不同手术方式对原发性肝癌患者血清炎症因子、肝功能及CRP等指标的影响

目的 比较腹腔镜肝切除术与传统开腹肝切除术治疗原发性肝癌患者的炎症因子、肝功能及c反应蛋白的差异。方法根据患者肝切除方式的不同,836例原发性肝癌患者分为腹腔镜肝切除术组(77例)和传统开腹肝切除术组(759例),对比分析两组患者的血清炎症因子、肝功能及C反应蛋白(CRP)水平的差异。结果在术前,两组患者的血清炎症因子、肝功能及CRP水平无统计学差异；而在术后1、3、7天,腹腔镜肝切除术患者的血清指标水平均显著低于传统开腹肝切除术组。结论对于原发性肝癌患者的治疗,相较传统开腹肝切除术,腹腔镜肝切除术引起的炎性应激以及肝脏损伤更轻。

Effects of different surgical methods on serum inflammatory factors,liver function and CRP in patients with primary liver cancer

Objective To compare the differences of inflammatory factors,liver function and C reactive protein in patients with primary liver cancer treated by laparoscopic hepatectomy and conventional open hepatectomy.Methods836 cases of primary liver cancer patients with liver resectiondivided into laparoscopic liver resection group (77 cases) and conventional open hepatectomy group (759 cases) according to the different operation ways,serum inflammatory factors,liver function and C reactive protein (CRP) were analyzed.ResultsBefore operation,there was no significant difference in serum inflammatory factor,liver function and CRP in the patients of the two groups,and after the day 1,3,7,serum indexes of laparoscopic liver resection group were significantly lower than traditional open liver resection group.ConclusionFor the treatment of primary liver cancer patients,compared with the traditional open hepatectomy,the inflammatory stress and liver damage caused by laparoscopic liver resection are lighter.