| 南海沿海海藻内生真菌ZJ27次级代谢产物研究 |
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| 引用本文： | Xiao BH,She ZG,Lei XL,Chen B,Huang CH,Xu J. 南海沿海海藻内生真菌ZJ27次级代谢产物研究[J]. 中药材, 2011, 34(4): 544-546 |
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| 作者姓名： | Xiao BH She ZG Lei XL Chen B Huang CH Xu J |
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| 作者单位： | 广东海洋大学食品科技学院;中山大学化学与化学工程学院; |
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| 基金项目： | 国家自然科学基金(20972197); 广东省自然科学基金(9151027501000055); 广东省科技计划项目(2010B030600004); 广东海洋大学基金(E09095) |
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| 摘 要： | 目的:对南海沿海海藻内生真菌ZJ27次级代谢产物进行研究。方法:采用色谱技术进行分离纯化,结合理化性质和波谱分析技术确定化合物的结构。结果:从真菌ZJ27次级代谢产物中分离得到5个化合物,分别为:核丛青霉素(1)、ochrephilone(2)、6-((3E,5E)-5,7-二甲基-2-酮基-3,5-壬二烯基)-2,4-二羟基-3-甲基苯甲醛(3)、(2E,4E)-4,6-二甲基-2,4-辛二烯酸(4)、pencolide(5)。结论:化合物1量特别大,达11 g,化合物2也有66 mg,因此本菌经优化培养可望成为药源微生物。
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| 关 键 词： | 海藻 内生真菌 次级代谢产物 |
Secondary metabolites of seaweed endophytic fungi ZJ27 in the South China Sea coast |
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| Xiao Bi-hong,She Zhi-gang,Lei Xiao-ling,Chen Bin,Huang Cai-huan,Xu Jia. Secondary metabolites of seaweed endophytic fungi ZJ27 in the South China Sea coast[J]. Journal of Chinese medicinal materials, 2011, 34(4): 544-546 |
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| Authors: | Xiao Bi-hong She Zhi-gang Lei Xiao-ling Chen Bin Huang Cai-huan Xu Jia |
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| Affiliation: | XIAO Bi-hong1,SHE Zhi-gang2,LEI Xiao-ling1,CHEN Bin2,HUANG Cai-huan1,XU Jia1(1.College of Food Science and Technology,Guangdong Ocean University,Zhanjiang 524025,China,2.College of Chemistry and Chemical Engineering,Sun Yat-sen University,Guangzhou 510275,China) |
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| Abstract: | Objective:To study the secondary metabolites of coastal seaweed endophytic fungi ZJ27.Methods:The compounds were isolated by chromatographic technique.The structures were identified by comprehensive physic-chemical properties and spectral methods.Results:Five compounds were isolated and identified as sclerotiorin(1),ochrephilone(2),6-((3E,5E)-5,7-dimethyl-2-methylenenona-3,5-dienyl)-2,4-dihydroxy-3-methylbenzaldehyde(3),(2E,4E)-4,6-dimethylocta-2,4-dienoic acid(4),pencolide(5).Conclusion:11 g of the compoun... |
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| Keywords: | Seaweed Endophytic fungi Secondary metabolites |
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