原发性胆囊癌与胆囊结石（附84例分析）

本文分析作者收治的８４例胆囊癌的临床特点并结合文献探讨胆囊结石的关系。目前尚无证据说明胆囊结石是胆囊癌的致癌因，但它在成癌过程中很可能起着促进作用。年龄超过５０岁、女性、合并胆囊炎或接触化学致癌物质可以认为是胆囊结石者易患胆囊癌的高危因素。在目前，早期诊断胆囊癌依然十分困难，治疗预后恶劣的情况下，对于具有高危因素者如不能确认胆囊形态正常，施行预防性胆囊切除是合理的。

Gallbladder cancer and gallstones.

y reporting 84 cases of primary carcinoma of thegallbladder we experienced and reviewing literatures.the relationship between gallbladder cancer and stonewas discussed. Although there is no evidence that gall-stone has carcinogenesis for gallbladder cancer nowa-days. the stone may play a role in promoting the malig-nant transformation. High risk factors leading gallblad-der cancer in patients with gallstone can be listed suchas with age over 50 years-old, female cholecystitis andexposure to chemical carcinogens. Since gallbladercancer is still extremely difficult to be diagnosed in itsearly stage and with poor prognosis. prophylactivecholecystectomy may be a reasonable procedure for thepatients with gallstone in high risk group unless a nor-mal gallbladder can be identified morphologically byultrasonography.