影响胃平滑肌肉瘤预后的因素及外科处理

本文分析了５０例经手术治疗的胃平滑肌肉瘤患者的临床病理特点及影响预后的因素，结果发现，胃平滑肌肉瘤的主要临床症状为腹痛和消化道出血。通过ＣＯＸ回归模型参数估计及显著性检验方法证实，本病预后与肿瘤大小、有无浸润邻近器官或转移，以及病理组织学分级明显相关，而与手术类型、切除范围、年龄、性别、局部浸润程度及肿瘤位置无密切关联。广泛的胃切除根治术中加宽无瘤边界以及区域淋巴结清扫并不优于局部切除术。

Prognostic factors and surgical treatments inleiomyosarcoma of the stomach.

here were 50 c8Res with leiomvosarcoma of thestomach (LMS) admitted to our hospital from January1966 to January 1994. The most presenting symptomsof LMS were abdominal pain and hemorrhage. Typesof operation we choosed as followed: palliative tumorresection, simple wedge resection of the stomach.subtotal gastrectomy or total gastrectomy and extended gastrectomy with block excision of portions of liver, spleen, pancreas.Through COX regression models and significancetest, we found the prognosis of LMS surviral rate wassignificantly correlated with tumor size, invasion of adjacent organs, metastasis and histopathologic grade.The ten years survival rate was 74% and the survivalrate of cess than two years 89%. It is revealed that theprognosis of extended gastrectomy and/or regionallymphonode clearance to treat LMs is not better thanthat of simple wedg resection of a limited portion ofthe stomach.