凝血四项检测在临产孕妇中的应用

摘要：目的探讨凝血四项在临产孕妇中检测的临床应用价值。方法选取2010年1月至2010年12月于本院产科门诊规律产检的健康临产孕妇（均为妊娠38周以后临产）157例（研究组），及同期在本院体检的健康未孕妇女108例（对照组）。采用全自动血凝仪对两组凝血酶原时间（prothrombintime，PT）、活化部分凝血活酶时间（activatedpartialthromboplastintime，APTF）、纤维蛋白原（fibrinogen，Fib）、凝血时间（thrombintime，’rr）进行检测，并相互比较。结果研究组PT、APTT比对照组明显缩短（PT：10．8±1．4／11．9±1．3。P〈0．05；APrrr：32．8±3．6／30．4±1．9，P〈0．05），Fib含量明显增加（4．3±0．23／2．8±0．53，P〈0．01），n1差异无统计学意义。结论晚孕妇女体内凝血时间、纤溶活性和抗凝成分均发生显著性改变，血液凝固性提高。因此产前及时检查凝血各项指标的变化对及时发现潜在的产科DIC意义重大。

Application of Coagulation Testing in the Parturient Women

Objective To investigate the clinical value of coagulation test used in the parturient women. Methods 157 cases of healthy parturient women （ labor 38 weeks later） were selected from January to December in 2010 in the mater- nity clinic department as the experimental group while 108 cases of non - pregnant women over the same period were chosen as the control group. The prothrombin time （PT）, activated partial thromboplastin time （AIYFF）, fibrinogen （Fib） and prothrombin tinle （TT） were detected by automatic coagulation analyzer, and compared with each other. Results PT and APTT in the experimental group were significantly shorter than that in the control group （ FF： 10. 8 ± 1.4/11.9 ± 1.3, P 〈0.05; APTT： 32.8±3.6/30.4 ± 1.9, P 〈0.05）. Fib significantly increased （4.3 ± 0.23/2.8 ± 0.53, P〈 0. 01 ）. There were no significant difference between the two groups. Conclusion Coagulation ability, fibrinolytic and ac- tivity anti - clotting components in the blood of parturient women change significantly, with blood coagulation improving. So prenatal examination of each index of blood coagulation is helpful to identify potential danger of obstetrics.