Colonic Adenomas in Asymptomatic Women with a History of Breast Cancer |
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| Authors: | Douglas K Rex MD FACG George W Sledge MD Patricia A Harper MD Thomas M Ulbright MD Patrick J Loehrer MD Debra J Helper MD Jennefer J Smith RN Maurits J Wiersema MD Robert H Hawes MD FACG Glen A Lehman MD FACG |
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| Institution: | Department of Medicine, Divisions of Gastroenterology, Hematology Oncology, and Department of Pathology, Indiana University School of Medicine, and the Indianapolis Breast Center, Indinapolis, Indiana |
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| Abstract: | One hundred ninety-three asymptomatic women with a personal history of breast cancer underwent screening colonoscopy. One hundred sixty-eight women had breast cancer as their only potential risk factor for colonic neoplasia, and 25 had a family history of colorectal neoplasia in addition to their personal history of breast cancer. Among women with breast cancer, increasing age and body weight were each predictive of an increasing prevalence of colonic adenomas. The prevalence of colonic adenomas in women aged 50–75 yr whose only potential risk factor was breast cancer was 18%, and was identical to the prevalence of colonic adenomas in 186 asymptomatic average-risk control women aged 50-75 yr (odds ratio 1.0. 95% CI 0.54-1.87). We conclude that a personal history of breast cancer does not predict a higher prevalence of colonic adenomas. |
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