| 疾病相关基因定位的全基因组扫描策略与方法 |
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| 引用本文： | 张安平,张学军,朱文元. 疾病相关基因定位的全基因组扫描策略与方法[J]. 疾病控制杂志, 2001, 5(2): 135-138 |
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| 作者姓名： | 张安平 张学军 朱文元 |
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| 作者单位： | 1. 安徽医科大学第一附属医院皮肤科,
2. 南京医科大学第一附属医院皮肤科, |
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| 摘 要： | 人类疾病均直接或间接与基因有关，复杂性状的多基因疾病相关基因的定位和遗传分析是近年来医学遗传学研究的热点和难点，全基因组扫描策略在此发挥了重要作用。
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| 关 键 词： | 基因定位 全基因组扫描 连锁分析 疾病 遗传病 |
| 文章编号： | 1008-6013(2001)02-0135-04 |
| 修稿时间： | 2000-09-30 |
The strategy of gene mapping and the approach to genome-wide search for human genetic diseases |
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| ZHANG Anping,ZHANG Xuejun,ZHU Wenyuan. The strategy of gene mapping and the approach to genome-wide search for human genetic diseases[J]. Chinese Journal of Disease Control and Prevention, 2001, 5(2): 135-138 |
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| Authors: | ZHANG Anping ZHANG Xuejun ZHU Wenyuan |
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| Abstract: | The great majority of human diseases are directly or i nd irectly associated with genes. Gene mapping and genetic analysis for human compl ex polygenic disorders has become a hot-spot and the neck of the bottle in the medical genetics research recently. The approach to genome-wide search has pla yed an important role in the respect. |
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