MO.MA球囊保护下近闭塞颈动脉支架成形术的临床研究

目的研究MO.MA球囊保护下颈动脉支架成形术(CAS)治疗近闭塞颈动脉的安全性、可行性及疗效。方法 2006年至2010年,共收治14例近闭塞颈动脉患者,狭窄程度95%～99%,所有病例可见侧支代偿。其中表现为短暂性脑缺血发作(TIA)者11例,表现为脑血栓形成者3例。所有患者均在MO.MA球囊保护下行CAS。对手术成功率、围手术期并发症、随访结果进行分析。结果手术成功率为100%。围手术期并发症2例,术中出现TTA发作,2 h后恢复正常。对患者进行随访3～30个月,平均(10.7±7.7)个月。4例行CTA或DSA随访,无再狭窄发生,无病变侧颈动脉脑卒中发生。结论 MO.MA球囊保护下CAS治疗近闭塞颈动脉安全、有效,无法耐受颈动脉血流阻断是主要的风险。

Stenting angioplasty with the help of MO.MA proximal cerebral protection device for the treatment of nearly-occluded carotid artery: a clinical study

Objective To assess the safety,feasibility and efficacy of carotid artery stenting(CAS) with the use of MO.MA proximal cerebral protection device for the treatment of nearly-occluded carotid artery. Methods During the period from 2006 to 2010,a total of 14 patients with nearly-occluded carotid artery (stenosis degree of 95%- 99%) were treated with CAS.The signs of collateral circulation were observed in all patients.The disease presented as transient insufficiency attack(TIA) in 11 patients and was manifested as cerebral thrombosis in 3 patients.CAS procedure was performed with the use of MO.MA proximal cerebral protection device in all patients.The success rate,perioperative complications and follow-up results were recorded and analyzed.Results The technical success rate was 100%.TIA occurred in two patients and the patients recovered two hours later.All the patients were followed up for 3-30 months with a mean of (10.7±7.7) months.Follow-up CTA or DSA after CAS was performed in 4 cases,and no re-stenosis was observed.No ipsilateral stroke occurred during the follow-up period.Conclusion Carotid artery stenting with the use of MO.MA proximal cerebral protection device is a safe and effective therapeutic option for nearlyoccluded carotid artery.Neurologic intolerance to carotid flow blockage is the main risk of this technique.