| 小儿巨细胞病毒感染142例临床分析 |
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| 引用本文： | 赵继顺,阮强,孙梅. 小儿巨细胞病毒感染142例临床分析[J]. 中国小儿急救医学, 2003, 10(3): 149-151 |
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| 作者姓名： | 赵继顺 阮强 孙梅 |
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| 作者单位： | 中国医科大学第二临床学院,辽宁,沈阳,110004 |
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| 基金项目： | 辽宁教育厅高等学校科学研究资助项目 (课题号 :2 0 12 12 69) |
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| 摘 要： | 目的 探讨小儿巨细胞病毒感染的临床特点及诊断手段。 方法 对 14 2名经尿CMV DNA及血清CMV IgM抗体测定确认为巨细胞病毒感染患儿的临床资料进行总结分析。 结果 用FQ PCR法反复多次检测尿中CMV DNA ,利用ELISA法检测血中CMV IgM抗体诊断CMV感染。 结论 巨细胞病毒感染以肝脏损害最多见 ,以神经系统缺陷为最严重 ,还可累及周身各脏器 ;FQ PCR法及ELISA法诊断CMV感染方便、敏感、有效
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| 关 键 词： | 巨细胞病毒 围生期 |
| 文章编号： | 1007-9459(2003)-03-0149-03 |
| 修稿时间： | 2002-12-23 |
The clinical analysis of 142 children with cytomegalovirus infection |
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| ZHAO Ji-shun,RUAN Qiang,SUN Mei. The clinical analysis of 142 children with cytomegalovirus infection[J]. Chinese Pediatric Emergency Medicine, 2003, 10(3): 149-151 |
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| Authors: | ZHAO Ji-shun RUAN Qiang SUN Mei |
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| Abstract: | Objective To discuss the clinical features and diagnostic methods in children's cytomegalovirus infection.Methods 142 children with cytomegalovirus infection were surveyed and analysed. The diagnosis were confirmed with detection of urine CMV-DNA and serum CMV-IgM antibody.Results The CMV infection was diagnosed by FQ-PCR method to detect CMV-DNA in urine and ELISA method was used to examine CMV-IgM antibody in blood.Conclusion Although all systems can be infected by CMV, liver has the maximal probability to be invaded. Among all systemic injuries caused by CMV,CNS defect is the most severe.FQ-PCR and ELISA are good methods to detect CMV infection with convenence, high efficiency and sensitivity. |
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| Keywords: | cytomegalovirus perinatal period |
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