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Incidence and outcome of early Candida peritonitis after liver and pancreas transplantation |
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| Authors: | Michele Bartoletti Carlos Cervera Irma Hoyo Laura Linares Gemma Sanclemente Jordi Bosch Francesc Marco Federico Cofán María José Ricart Miquel Navasa Asunción Moreno |
| Institution: | 1. Service of Infectious Diseases, Hospital Clinic of Barcelona, IDIBAPS, Barcelona, Spain;2. Department of Clinical Microbiology, Hospital Clinic, School of Medicine, University of Barcelona, Barcelona, Spain;3. Barcelona Centre for International Health Research (CRESIB, Hospital Clínic‐Universitat de Barcelona), Barcelona, Spain;4. Renal Transplant Unit, Hospital Clinic of Barcelona, IDIBAPS, Barcelona, Spain;5. Liver Transplant Unit, Hospital Clinic of Barcelona, IDIBAPS, Barcelona, Spain;6. Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBERehd), Barcelona, Spain |
| Abstract: | Candida peritonitis is a potentially life‐threatening infection after abdominal transplantation, although there is scant information regarding its incidence and outcome. We analysed the incidence rate and outcome of Candida peritonitis in 717 liver or pancreas transplant recipients. Five cases of Candida peritonitis were diagnosed, representing the second most frequent cause of invasive fungal infection in the cohort. The incidence rate of Candida peritonitis during the first 30 days after transplantation was 6.5 cases/10 000 transplant days in pancreas recipients and 1.2 cases/10 000 transplant days in liver recipients (P = 0.035). Four of the five patients received an echinocandin in combination with other antifungal. All patients were alive and with good graft function at 1‐year follow‐up. In our series, Candida peritonitis in liver and pancreas transplant recipients was not uncommon and had a good prognosis. |
| Keywords: | Candida spp peritonitis antifungal agents |