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Photopatch testing: recommendations for a European photopatch test baseline series
Authors:Margarida Gonçalo  James Ferguson  Annie Bonevalle  Derk P Bruynzeel  Ana Giménez‐Arnau  An Goossens  Alastair Kerr  Mario Lecha  Norbert Neumann  Bo Niklasson  Paolo Pigatto  Lesley E. Rhodes  Thomas Rustemeyer  Robert Sarkany  Pierre Thomas  Mark Wilkinson
Affiliation:1. Department of Dermatology, Coimbra University Hospital, Faculty of Medicine, University of Coimbra, 3000‐075 Coimbra, Portugal;2. Photobiology Unit, Ninewells Hospital and Medical School, DD1 9SY Dundee, Scotland;3. Hopital Claude Huriez, Lille, France;4. VU University Medical Centre, Amsterdam, The Netherlands;5. Hospital del Mar, Universitat Autónoma and Universitat Pompeu Faba, Barcelona, Spain;6. University Hospital, Leuven, Belgium;7. University of Barcelona, Barcelona, Spain;8. Heinrich‐Heine University, Dusseldorf, Germany;9. Chemotechnique Diagnostics, Vellinge, Sweden;10. Galeazzi Hospital, Department of Technologies for Health, University of Milan, Milan, Italy;11. University of Manchester, Salford Royal Foundation Hospital, Manchester, UK;12. St John's Institute of Dermatology, London, UK;13. Department of Dermatology, Leeds Teaching Hospitals NHS Trust, UK
Abstract:In order to establish a consensus recommendation for performing photopatch testing, a photopatch test taskforce group was established under the joint umbrella of the European Society for Contact Dermatitis and the European Society for Photodermatology in 2000. After proposing the most adequate methodology in 2004 and completing a European multicentre photopatch test study in 2011, this taskforce is recommending a list of photoallergens that should form part of a baseline series for photopatch testing in Europe. It contains mainly ultraviolet filters and drugs, mostly non‐steroidal anti‐inflammatory drugs. The choice of chemicals was based on the results of a recent multicentre study, previous published cases of photoallergy, and use of the substances in the European market. It is suggested that an extended list of photoallergens should be photopatch tested in selected cases, along with patients' own products. Two contact allergens, cinnamyl alcohol and decyl glucoside, should be simultaneously patch tested in order to clarify photopatch and patch test reactions, respectively, to ketoprofen and methylene bis‐benzotriazolyl tetramethylbutylphenol (Tinosorb M?).
Keywords:baseline series  NSAIDs  photoallergens  photopatch test  UV filters
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