Medication adherence feedback intervention predicts improved human immunodeficiency virus clinical markers

Thirty‐three participants in a human immunodeficiency virus (HIV) medication adherence feedback (MAF) intervention were compared with 58 HIV‐positive non‐participants in laboratory‐tested CD4 and viral load. The intervention provided adherence feedback and counselling based on a visual display from an electronic pill bottle (MEMS^TM). Multiple regression controlling for baseline CD4 and showed that postintervention CD4 was higher for MAF participants than for non‐MAF participants. Non‐MAF participants' CD4 significantly declined over time. MAF participants were also less likely than non‐MAF participants to have a detectable postintervention viral load.