| 双柱双pH固相萃取和毛细管气相色谱法同时快速测定血浆中酸性和碱性药物 |
| |
| 引用本文： | 邱丰和,刘力,罗毅,卢涌泉.双柱双pH固相萃取和毛细管气相色谱法同时快速测定血浆中酸性和碱性药物[J].药学学报,1996,31(3):205-208. |
| |
| 作者姓名： | 邱丰和 刘力 罗毅 卢涌泉 |
| |
| 作者单位： | 军事医学科学院毒物药研究所，北京 100850 |
| |
| 摘 要： | 报道了一种能同时快速测定血浆中酸性和碱性药物的固相萃取毛细管气相色谱法。在自制的并联双柱萃取装置上,两柱可在不同的pH下操作,分别提取酸性和碱性药物。通过对6类8种酸性和碱性药物的定性和定量实验表明,该法快速、灵敏。
|
| 关 键 词： | 双柱双pH固相萃取法 毛细管气相色谱 |
| 收稿时间： | 1995-03-20 |
A DOUBLE COLUMN DOUBLE pH SOLID PHAES EXTRACTION AND CAPILLARY GC/FID METHOD FOR RAPID SIMULTANEOUS DETERMINATION OF ACIDIC AND BASIC DRUGS IN HUMAN PLASMA |
| |
| FH Qiu,L Liu,Y Luo and YQ Lu.A DOUBLE COLUMN DOUBLE pH SOLID PHAES EXTRACTION AND CAPILLARY GC/FID METHOD FOR RAPID SIMULTANEOUS DETERMINATION OF ACIDIC AND BASIC DRUGS IN HUMAN PLASMA[J].Acta Pharmaceutica Sinica,1996,31(3):205-208. |
| |
| Authors: | FH Qiu L Liu Y Luo and YQ Lu |
| |
| Abstract: | A capillary gas chromatographic method for the rapid simultaneous iden tificationand quantitation of acidic and basic drugs in human plasma is presented,A special double column solidphase extraction device was designed ,in which two X-5 resin columns can extract drugs at differentpH,The detection limits for acidic and hasic drugs can reach 0.5μg·ml-1,while the time needed isonly half of that when using commercial solid phase extraction cartridges. |
| |
| Keywords: | Double column double pH solid phase extraction Capillary GC/FID |
| 本文献已被 维普 等数据库收录！ |
| 点击此处可从《药学学报》浏览原始摘要信息 |
| 点击此处可从《药学学报》下载免费的PDF全文 |
|
