| 536例下呼吸道感染患者病原菌及耐药分析 |
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| 引用本文： | 石敦义,李勇朴,夏维,甘洪,杨梅,贾翼川. 536例下呼吸道感染患者病原菌及耐药分析[J]. 抗感染药学, 2011, 8(4): 279-282. DOI: 10.3969/j.issn.1672-7878.2011.04-018 |
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| 作者姓名： | 石敦义 李勇朴 夏维 甘洪 杨梅 贾翼川 |
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| 作者单位： | 重庆市长寿区人民医院呼吸内科,重庆,401220 |
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| 摘 要： | 目的:分析下呼吸道感染(lower respiratory infection,以下简称LRI)患者的病原菌种类分布及其耐药性,为合理用药提供参考。方法:采用WHONET-4软件分析2008—2010年期间住院的536例LRI患者病原菌分布及耐药情况。结果:536例患者中经培养分离出370株病原菌,其中,革兰阴性菌57.30%(212株),革兰阳性菌15.68%(58株),真菌27.02%(100株);病原菌按检测率排序依次是肺炎克雷伯杆菌52株(14.05%),白色念株菌43株(11.62%),鲍曼不动杆菌35株(9.46%),大肠埃希菌33株(8.92%),克柔假丝酵母菌23株(6.22%),铜绿假单胞菌18株(4.86%),曲霉菌18株(4.86%),肺炎链球菌16株(4.32%)。药物敏感试验显示:致病菌对常用抗菌药的耐药性普遍升高,但对阿莫西林/克拉维酸钾、哌拉西林/他唑巴坦、阿米卡星及亚胺培南较敏感。结论:LRI病原菌以革兰阴性菌为主,主要的病原菌对临床常用抗菌药物耐药严重。
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| 关 键 词： | 下呼吸道感染 病原菌 抗菌药物 耐药性 |
Distribution and Resistance of Pathogenic Bacteria in 536 Patients of Lower Respiratory Infections |
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| SHI Dun-yi,LI Yong-pu,XIA Wei,GAN Hong,YANG Mei,JIAYi-chuan. Distribution and Resistance of Pathogenic Bacteria in 536 Patients of Lower Respiratory Infections[J]. Anti-infection Pharmacy, 2011, 8(4): 279-282. DOI: 10.3969/j.issn.1672-7878.2011.04-018 |
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| Authors: | SHI Dun-yi LI Yong-pu XIA Wei GAN Hong YANG Mei JIAYi-chuan |
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| Affiliation: | SHI Dun-yi*,LI Yong-pu,XIA Wei,GAN Hong,YANG Mei,JIA Yi-chuan Department of Respiration,People's Hospital of Changshou district,Chongqing 401220,China |
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| Abstract: | Objective: To analyse the distribution and drug resistance of the pathogenic bacteria in the patients with lower respiratory infection(LRI) and to provide the reference for rational use of the drugs. Methods: Using the software WHONET-4, to analyse the pathogenic bacteria distribution and resistance of 536 inpatients from 2008 to 2010. Results: Out of 536 inpatients with LRI, 370 strains of pathogenic bacteria were isolated. including 212 strains of Gram-negative bacteria(57.30%), 58 strains of Gram-positiv... |
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| Keywords: | lower respiratory infection pathogen antibiotic drug resistance. |
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