| 反相高效液相色谱法优选黄芩中黄芩苷的提取工艺 |
| |
| 引用本文： | 张凤梅. 反相高效液相色谱法优选黄芩中黄芩苷的提取工艺[J]. 药学实践杂志, 2008, 26(5): 359-361 |
| |
| 作者姓名： | 张凤梅 |
| |
| 作者单位： | 北京市药品监督管理局药品认证管理中心,北京,100053 |
| |
| 摘 要： | 目的:研究黄芩中黄芩苷的最佳提取工艺.方法:采用L9(34)正交试验法考察黄芩中黄芩苷提取的各影响因素(A乙醇浓度、B提取时间、C容积量),以黄芩苷含量为指标进行直观分析及方差分析,确定最佳提取工艺.结果:黄芩中黄芩苷的最佳提取工艺条件为A1B3C3,即50%乙醇、热回流提取3 h、12倍药材量的乙醇.结论:此提取工艺简单易行,稳定可行,适于黄芩的大规模提取.
|
| 关 键 词： | 黄芩 黄芩苷 正交试验 高效液相色谱 |
| 收稿时间： | 2008-03-28 |
Optimization of extraction technology of baicalin in radix scutellariae by RP-HPLC |
| |
| Zhang Feng-mei. Optimization of extraction technology of baicalin in radix scutellariae by RP-HPLC[J]. The Journal of Pharmaceutical Practice, 2008, 26(5): 359-361 |
| |
| Authors: | Zhang Feng-mei |
| |
| Affiliation: | Certification Committee for Drugs of Beijing Drug Administration,Beijing 100053,China |
| |
| Abstract: | Objective:To study the extraction technology of baicalin in radix scutellariae.Methods:The L_9(3~4) orthogonal table was employed to speculate the influence factors of the extraction by means of inspecting alcohol concentration,extracting time and sol- vent volumn,which were the major three influenec factors.Then intiutive analysis and variance analysis were used to review the index of baicalin contents,by which the optimum extraction technology could be selected.Results:The optimum extraction technology we... |
| |
| Keywords: | radix scutellariae baicalin Orthogonal design HPLC |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
| 点击此处可从《药学实践杂志》浏览原始摘要信息 |
|
点击此处可从《药学实践杂志》下载全文 |
