Flow cytometry characterization of leukemic phase of nasal NK/T-cell lymphoma in tumor biopsies and peripheral blood |
| |
Authors: | Falcão Roberto P Rizzatti Edgar G Saggioro Fabiano P Garcia Aglair B Marinato André F Rego Eduardo M |
| |
Institution: | Center for Cell-Based Therapy, Department of Clinical Medicine, School of Medicine-USP, Ribeir?o Preto, SP, Brazil. |
| |
Abstract: | We report the findings of the immunophenotypic profile of three cases of nasal T/NK cell lymphoma in leukemic phase. Flow cytometry analysis was carried out using cell suspensions of tumor nasal biopsies and peripheral blood. Tumor samples were composed by a mixture of a predominant subset of medium-size true NK cytCD3epsilon-, sCD3epsilon-, CD56+ cells mixed with a minor subset of medium-size T/NK sCD3epsilon+, CD56+ cells. Both subsets were also detected in peripheral blood. In addition, an infiltration of small-size sCD3epsilon+, CD56- normal T lymphocytes was also present. |
| |
Keywords: | |
本文献已被 PubMed 等数据库收录! |
|