| 早期应用替罗非班对急性心肌梗死急症PCI术后C反应蛋白水平的影响 |
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| 引用本文： | 肖红兵,顾俊,张大东. 早期应用替罗非班对急性心肌梗死急症PCI术后C反应蛋白水平的影响[J]. 介入放射学杂志, 2010, 19(2): 101-104 |
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| 作者姓名： | 肖红兵 顾俊 张大东 |
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| 作者单位： | 上海瑞金医院集团闵行医院心内科,201100;上海瑞金医院集团闵行医院心内科,201100;上海瑞金医院集团闵行医院心内科,201100 |
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| 摘 要： | 目的探讨急性心肌梗死(AMI)患者急症冠状动脉介入治疗(PCI)不同时间应用替罗非班对于术后CRP水平和预后的影响。方法选择急症入院的84例AMI患者随机分为早期治疗组(n=45)与晚期治疗组(n=39),早期治疗组于急症入院即刻静脉给予替罗非班;晚期治疗组于冠状动脉造影后静脉给予替罗非班。比较两组患者PCI术前、术后的TIMI血流分级;测定PCI术前、术后3dCRP水平;记录住院期间及随访3个月时的主要心血管事件(MACE)的发生率。结果早期治疗组术前TIMI前向血流达到3级的比率明显高于晚期治疗组,而术后无差异;早期治疗组术后3d的CRP水平明显低于晚期组;两组术后住院期间MACE事件有明显差异,而随访3个月期间则无差异。结论AMI患者入院时尽早应用替罗非班对急症PCI治疗是安全有效的,且能够明显改善靶血管前向血流TIMl分级,降低CRP水平,减少住院期间心血管事件。
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| 关 键 词： | 心肌梗死 血管成形术 替罗非班 |
The effect of early application of Tirofiban on CRP levels in patients with acute myocardial infarction after emergency percutaneous coronary intervention |
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| XIAO Hong-bing,GU Jun,ZHANG Da-dong. The effect of early application of Tirofiban on CRP levels in patients with acute myocardial infarction after emergency percutaneous coronary intervention[J]. Journal of Interventional Radiology, 2010, 19(2): 101-104 |
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| Authors: | XIAO Hong-bing GU Jun ZHANG Da-dong |
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| Affiliation: | XIAO Hong-bing,GU Jun,ZHANG Da-dong.Department of Cardiology,Central Hospital of Minhang District,Ruijin Hospital Group,Shanghai 201100,China |
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| Abstract: | Objective To evaluate the effect of Tirofiban on CRP levels in patients with acute myocardial infarction(AMI) after primary emergency percutaneous coronary intervention(PCI).Methods Eighty-four AMI patients admitted on emergency were randomly divided into two groups:(1) early-treated group(n = 45), immediately receiving Tirofiban intravenously on admission and(2) late-treated group(n = 39), receiving Tirofiban intravenously after coronary angiography was performed.TIMI grading before and after PCI in both g... |
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| Keywords: | myocardial infarction angioplasty Tirofiban |
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