Miller Fisher综合征14例报道

目的:分析14例Miller Fisher综合征的临床特点和预后。方法:回顾性分析1998年1月至2007年3月我院收治的14例Miller Fisher综合征患者,应用Microsoft Access 2003建立数据库,分析患者的各种症状、体征和各项检查和预后。结果:病前感染者11例,其中肠道感染8例,双侧动眼神经损害14例,眼内肌的损害7例,对光反射消失5例,共济失调9例,头晕7例,腱反射减低12例,肌力减退7例,周围神经损害5例,病理征3例,蛋白-细胞分离12例,影像学异常2例,肌电图改变7例。结论:Miller Fisher综合征临床症状复杂,可在经典的三联征基础上伴有其他体征,也可仅有其中的两联征,预后较好。

Miller Fisher syndrome: 14 eases report

Objective:To analysis the clinical features and prognosis of patients with Miller Fisher syndrome.Method: The inpatients with Miller Fisher syndrome from January 1998 to March 2007 were retrospectively reviewed.A database was made with Microsoft Access 2003,include clinical symptoms,signs,all kind of examination,and prognosis.Results: Of all the cases,11 patients were precede by infection,14 patients had diplopia,9 patients had ataxia,7 patients had diz- ziness,12 patients had areflexia,7 patients had internal ophthalmoplegia,5 patients had disappeared light reflex,7 pa- tients had reduced muscle force,5 patients had peripheral lesion,3 patients had Babinski sign,12 patients had protein-cell separation,2 patients had abnormal image,7 patients had abnormal electromyography.Conclusion:Miller Fisher syn- drome had a complex clinical features,often occurred in addition to the characteristic triad or only occurred two symp- toms.The prognosis of Miller Fisher syndrome is well.