Humoral Immune Response to the Antigen Administered as an Immune Complex |
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| Authors: | M. Maru&#x i&#x S. Maru&#x i&#x -gale&#x i&#x B. Pokri&#x |
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| Affiliation: | Medical Center Paprikovac, Banja Luka, Bosnia. |
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| Abstract: | Antigen (HSA) bound in immune complexes at equivalence with syngeneic anti-HSA antibodies elicit much stronger humoral immune response then soluble HSA. On the other hand, administration of immune complexes formed with xenogeneic (rabbit) anti-HSA antibodies suppressed humoral immune response against HSA, but not against rabbit IgG in mice. We suggest that immunization with antigen bound in immune complex might represent a powerful tool in enhancing humoral immune responses. |
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