| 低硒并低铬对大鼠心肌细胞电生理的影响 |
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| 引用本文： | 段耀奎 曹文华. 低硒并低铬对大鼠心肌细胞电生理的影响[J]. 微量元素与健康研究, 1999, 16(1): 1-3 |
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| 作者姓名： | 段耀奎 曹文华 |
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| 作者单位： | 泰山医学院生理教研室，泰山医学院附院内一科 |
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| 摘 要： | 为进一步阐明克山病心肌细胞损害的机理，用细胞内微电极技术分别观察了正常对照、低Ｓｅ、单纯低Ｃｒ、低Ｓｅ低Ｃｒ饲料饲养１４周后大鼠心肌细胞电生理的改变。结果表明：单纯低铬组无变化；单纯低硒组静息电位（ＲＰ），电位幅度（ＡＰＡ）降低，电位时程（ＡＰＤ５０、ＡＰＤ９０）延长；低硒并低铬组ＲＰＡＰＡ降低，ＡＰＤ５０、ＡＰＤ９０明显延长。提示：缺硒并低铬可明显改变心肌细胞的电生理特性
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| 关 键 词： | 硒 铬 心肌电生理 |
Effects of selenium and chromium on the electrophysiology of myocardial cells of the rats |
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| Duan Yaokui Cao Wenhua Gai Jinfang et al. Effects of selenium and chromium on the electrophysiology of myocardial cells of the rats[J]. Studies of Trace Elements and Health, 1999, 16(1): 1-3 |
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| Authors: | Duan Yaokui Cao Wenhua Gai Jinfang et al |
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| Affiliation: | Dept of physiology Taishan Medical College TaiAn 271000 |
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| Abstract: | To elucidate the etiology of the impairment of myocardial cells in keshan disease,With intracellular microelectrode technigue,we observed the electrophysiological changes of the four groups of rats fed seperately with:normal,low se,low Cr and low Se low Cr fodder.Compared with the control,there is no change in low Cr group;However,in low Se group,RP and APA decreased,APD 50 and APD 90 prolonged;In low Se low Cr group,APA decreased,APD 50 and APD 90 Prolonged significantly.It suggested that Se and Cr deficiency jointly may change the electrophysiology of myocardial cells significantly. |
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| Keywords: | Selenium Chromium Electrophysiololgy of myocardial cells |
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