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Asymmetric dimethylarginine determines the improvement of endothelium-dependent vasodilation by simvastatin: Effect of combination with oral L-arginine
Authors:Böger Gerhild I  Rudolph Tanja K  Maas Renke  Schwedhelm Edzard  Dumbadze Ekaterina  Bierend Anneke  Benndorf Ralf A  Böger Rainer H
Affiliation:Clinical Pharmacology Unit, Institute of Experimental and Clinical Pharmacology, Hamburg, Germany.
Abstract:
Keywords:ADMA, asymmetric dimethylarginine   eNOS, endothelial nitric oxide synthase   FMD, flow-mediated dilation   HMG-CoA, 3-hydroxy-3-methylglutaryl coenzyme A   LDL, low-density lipoprotein   NO, nitric oxide   SR, sustained release
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