家猪贯穿缝合式胰肠吻合实验模型的建立

目的 建立家猪贯穿缝合式胰肠吻合的动物实验模型.方法 选取10头小型家猪,全麻后剖腹暴露胰腺,于胰腺左叶肠系膜上血管水平横断胰腺,胰腺近侧残端缝闭,远侧残端与空肠行端侧贯穿缝合式胰肠吻合,Roux-en-Y式重建消化道.结果 10头家猪行贯穿缝合式胰肠吻合手术均获成功.胰腺残端横径平均2.5 cm,胰管直径平均1.5 mm.手术时间为1.0～2.5 h,平均1.8h,其中胰肠吻合时间平均为8 min.术中平均出血量为25 ml.术后2头猪发生腹泻,1头猪发生切口感染,均经相应处理后治愈.术中未发生意外,术后未发生胰瘘,无死亡.结论 成功建立家猪贯穿缝合式胰肠吻合的实验模型.

Establishment of a porcine model of penetrating-suture pancreaticojejunostomy

Objective To establish a porcine model of penetrating-suture pancreaticojejunostomy. Methods Ten domestic pigs were selected, and after general anesthesia they underwent laparotomy and the pancreas was visualized. Then the pancreas was dissected at the level of superior mesenteric vascular, and the proximal pancreatic stump was sewed up. The anastomosis between the distal pancreatic stump and the intestinal wall adopted penetrating-suture pancreaticojejunostomy; the digestive tract was reconstructed by Roux-en-Y. Results The anastomosis with penetrating-suture pancreatieojejunostomy was successful in ten domestic pigs. The mean pancreatic stump diameter was 2.5 era, and the mean pancreatic duet diameter was 1.5 mm, the mean time for operation was 1.0 - 2.5 h, and the average time of pancreaticojejunostomy was 8 minutes. The mean blood loss was 25 ml. After operation, diarrhea occurred in 2 pigs and wound infection occurred in 1 pig, and all were cured with appropriate management. No pig died intra-operatively, and no pancreatic fistula or death occurred after operation. Conclusions A porcine model of penetrating-suture pancreaticojejunostomy is successfully established.