| 进展期胃癌根治术患者预后危险因素分析 |
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| 引用本文： | 陈千益,欧敬民,庄鹏远,穆嘉盛,忻卫平,刘颖斌.进展期胃癌根治术患者预后危险因素分析[J].东南大学学报(医学版),2011,30(6):909-914. |
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| 作者姓名： | 陈千益 欧敬民 庄鹏远 穆嘉盛 忻卫平 刘颖斌 |
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| 作者单位： | 1. 上海市杨浦区老年医院,普外科,上海,200090
2. 上海交通大学医学院附属新华医院,普外科,上海,200092 |
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| 摘 要： | 目的:探讨影响进展期胃癌患者根治术预后的相关危险因素。方法:回顾性分析675例进展期胃癌患者行根治术后的临床资料,采用Kaplan-Meier单因素分析法和Cox比例风险模型多因素方法分析。结果:全组术后1、3、5年累积复发率分别为27.7%、67.9%和84.4%,中位复发时间为31.7个月。其中局部复发占29.1%,腹膜复发占52.6%,血源性复发占18.3%。1、3、5年总体生存率分别为88.2%、54.5%和36.7%。单因素分析显示肿瘤Borrmann分型、浸润深度、淋巴结转移、组织学类型、TNM分期、切缘情况及是否接受辅助放化疗是影响患者预后的因素(P<0.05)。多因素分析表明组织学类型、TNM分期、切缘情况是影响进展期胃癌根治性切除术后预后的独立危险因素(P<0.05)。结论:组织学类型、TNM分期、切缘情况是进展期胃癌根治性切除术后影响生存的独立危险因素;D2根治性切除进展期胃癌结合辅助性放化疗可进一步改善患者预后。
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| 关 键 词： | 进展期胃肿瘤 根治术 预后 危险因素 |
Risk factors of prognosis on advanced gastric cancer patients after surgical radical resection |
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| CHEN Qian-yi,OU Jing-min,ZHUANG Peng-yuan,MU Jia-sheng,XIN Wei-ping,LIU Ying-bin.Risk factors of prognosis on advanced gastric cancer patients after surgical radical resection[J].Journal of Southeast Univ: Medical Sci Ed,2011,30(6):909-914. |
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| Authors: | CHEN Qian-yi OU Jing-min ZHUANG Peng-yuan MU Jia-sheng XIN Wei-ping LIU Ying-bin |
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| Institution: | CHEN Qian-yi1,OU Jing-min2,ZHUANG Peng-yuan2,MU Jia-sheng2,XIN Wei-ping1,LIU Ying-bin2(1.Department of General Surgery,Yangpu Geriatric Hospital,Shanghai 200090,China,2.Department of General Surgery,Xinhua Hospital Affiliated to Shanghai Jiaotong University School of Medicine,Shanghai 200092,China) |
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| Abstract: | Objective: To explore risk factors of prognosis on advanced gastric cancer patients after surgical radical resection and study its impact on patients long-term prognosis.Methods: Clinical data were analyzed from 675 patients who underwent surgical radical resection for advanced gastric cancer.Potential clinicopathological prognostic factors were examined by Kaplan-Meier univariate and Cox proportional hazards model regression multivariate analysis.Results: The 1,3 and 5 years cumulative recurrence rate was ... |
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| Keywords: | advanced gastric neoplasms radical mastectomy prognosis risk factor |
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