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无抽搐电休克治疗对认知功能的影响
引用本文:钱卫娟,范俭雄,周群,高晓宁. 无抽搐电休克治疗对认知功能的影响[J]. 四川精神卫生, 2009, 22(2): 78-80
作者姓名:钱卫娟  范俭雄  周群  高晓宁
作者单位:南京医科大学附属脑科医院,210029
基金项目:南京医科大学科技发展基金 
摘    要:目的评价无抽搐电休克治疗(MECT)对认知功能的影响。方法对24例精神疾病患者在MECT前及MECT后5—7天内进行威斯康星卡片分类、连线试验A和B、数字广度、数字符号和临床记忆量表等神经心理学测验。结果①威斯康星卡片分类中,患者完成的总应答数(Ra)在MECT治疗后较治疗前显著减少(P〈0.05);②连线试验A和B中,患者完成时间在MECT治疗后较治疗前显著缩短(P〈0.05);③数字广度中,患者在MECT治疗后较治疗前显著增加(P〈0.05);④数字符号中,患者在MECT治疗后较治疗前差异无显著性(P〉0.05);⑤临床记忆量表中各项指标,患者在MECT治疗后较治疗前差异均无显著性(P均〉0.05);⑥精神疾病患者在MECT治疗后精神症状得到控制,病情恢复良好。结论MECT对认知功能无明显损害,对重性精神障碍患者疗效好。

关 键 词:无抽搐电休克治疗  神经心理学测验  认知功能

The effects of modified electric convulsive therapy on cognitive function
Affiliation:QIAN Weijuan,FAN Jianxiong,ZHOU Qun, et al.( Nanjing Brain Hospital Affliated to Nanjing Medical University,Jiangsu 210029, China)
Abstract:Objective To estimate the effects of modified electric convulsive therapy(MECT) on cognitive function. Method Twenty- four participants were assessed by Wisconsin Card Sorting Test (WCST), trail making test A and B, Digit Span Test( DST), Digit -Symbol Substitution Test and Clinical Memory Score(CMS) at pre - and post - MECT. Results The total trials of WCST were significantly reduced at post - treatment than pre - treatment ( P 〈 0.05 ) ; In trail making test A and B,the finished - time was significantly shorter at post - treatment than pre - treatment ( P 〈 0. 05 ) ; In DST, there were significantly improved after treatment than before( P 〈 0. 05 ) ;No significant difference was observed between pre -treatment and post- treatment in Digit -Symbol Substitution Test( P 〉0. 05 ) ;No significant difference was observed between pre- treatment and post- treatment in the Clinical Memory Score( all P 〉 0. 05 ) ;Psychiatric symptoms were well- controlled and pathogenetic condition had good improvement. Conclusion MECT do not damage the cognitive function signifieantly;MECT have good therapeutic effect on multiplicity mental disorder patients.
Keywords:Modified electric convulsive therapy(MECT) Neruropsyehology tests Cognitive function
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