| 芪参复康胶囊对衰老模型小鼠单胺类神经递质的影响 |
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| 引用本文： | 李新田,杨来启,林昱,史锋庆,邱财荣,薛欣.芪参复康胶囊对衰老模型小鼠单胺类神经递质的影响[J].华西药学杂志,2008,23(6). |
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| 作者姓名： | 李新田 杨来启 林昱 史锋庆 邱财荣 薛欣 |
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| 作者单位： | 解放军第三医院药剂科,陕西,宝鸡,721004 |
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| 基金项目： | 全军"十一五"医药卫生科研专项基金课课
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| 摘 要： | 目的 探讨中药芪参复康胶囊(QSFK)对D-半乳糖致衰老模型小鼠单胺类神经递质的影响.方法 用D-半乳糖制备小鼠衰老模型,QSFK灌服6周,用荧光法检测去甲肾上腺素、多巴胺、5-羟色胺、5-羟吲哚乙酸含量的变化.结果 QSFK能明显提高D-半乳糖致衰老模型小鼠脑组织中单胺类神经递质的含量,中、大剂量组作用显著,小剂量组作用不明显.结论 QSFK具有明显的抗衰老作用.
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| 关 键 词： | 芪参复康胶囊 致衰老小鼠 单胺类神经递质 荧光法 |
Effect of Qishen Fukang capsule on monoamine neurotransmitter in aging mice |
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| LI Xin-tian,YANG Lai-qi,LIN Yu,SHI Feng-qing,QIU Cai-rong,XUE Xin.Effect of Qishen Fukang capsule on monoamine neurotransmitter in aging mice[J].West China Journal of Pharmaceutical Sciences,2008,23(6). |
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| Authors: | LI Xin-tian YANG Lai-qi LIN Yu SHI Feng-qing QIU Cai-rong XUE Xin |
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| Institution: | LI Xin-tian,YANG Lai-qi,LIN Yu,SHI Feng-qing,QIU Cai-rong,XUE Xin ( Department of Pharmacy,the 3rd Hospital of PLA,Baoji 721004,China) |
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| Abstract: | OBJECTIVE To explore the effect of Qishen Fukang capsule on the contents of monoamine neurotransmitter in the aging mice induced by D-galactose.METHODS Aging mice induced by D-galactose were given Qishen Fukang capsule for 6 weeks to detect the changes of noradrenaline,dopamine,5-HT and 5-hydroxyindole acetic acid by fluorometric method.RESULTS Qishen Fukang capsule significantly increased the contents of monoamine neurotransmitter in cerebral tisssue of the aging mice,especially the effect of middle and hi... |
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| Keywords: | Qishen Fukang capsule Aging mice Monoamine neurotransmitter Fluorometric method |
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