我院108例药品不良反应报告分析

目的 了解本院药品不良反应（ADR）发生的特点和规律。方法 选取108例ADR报告,按患者的性别、年龄、给药途径、累及的器官及临床表现等进行统计分析。结果 108例ADR报告中,男女比例为1：1.84;静脉引起的ADR最多,占90.74%;涉及药品34种;ADR主要是由抗菌药物和中药注射剂引起的,分别占40.74%和33.33%;ADR的临床表现主要为皮肤及其附件的损害为主,占39.29%。结论 加强和重视ADR的监测工作,规范临床用药,减少或避免不良反应的发生。

Analysis of 108 cases of adverse drug reactions in our hospital

Objective To investigate the characteristics and regular pattern of the adverse drug reactions. Methods Statistically analyzed, 190 cases of ADR reports collected in our hospital according to the age, gender and intake of medication. Results The male to female ration was 1：1.8 of 108 cases; most of the ADR was induced by venous transfusion 90.74%; the ADR were induced predominantly by the anti-microbial agents and TCM injection, 40.74% and 33.33 respectively; the ADR of 108 cases manifested chiefly as lesions of skin and its appendages, 39.29%. Conclusion Great importance should attach to ADR monitoring, so as to reduce or avoid repeated occurrence of ADR.