| 肿瘤标志物蛋白芯片中肺癌相关指标的筛选优化 |
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| 引用本文： | 赵顺林,胡卫东,徐闻博,刘越,吴洲清.肿瘤标志物蛋白芯片中肺癌相关指标的筛选优化[J].重庆医科大学学报,2011,36(11):1353-1356. |
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| 作者姓名： | 赵顺林 胡卫东 徐闻博 刘越 吴洲清 |
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| 作者单位： | 1. 武汉市江夏区第一人民医院肿瘤科,武汉,430020
2. 武汉大学中南医院肿瘤科,湖北省肿瘤医学临床研究中心,肿瘤生物学行为湖北省重点实验室,武汉430071 |
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| 基金项目： | 湖北省自然科学基金资助项目(编号:2010CDB05502); 肿瘤生物学行为湖北省重点实验室科研启动基金资助项目 |
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| 摘 要： | 目的:分析多种肿瘤标志物(Tumor marker,TM)与肺癌的相关性,筛选相关指标,为建立检测肺癌的小型蛋白芯片提供依据.方法:使用TM蛋白芯片系统,检测311例肺癌患者血清中多种TM:癌抗原125(Cancer antigen 125,CA125)、癌抗原153(Cancer antigen 153,CA153)...
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| 关 键 词： | 肿瘤标志物 肺癌 诊断 |
Screening and optimizing the lung cancer related tumor markers from multi-tumor marker protein chip |
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| ZHAO Shun-lin
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HU Wei-dong
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XU Wen-bo
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LIU Yue
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WU Zhou-qing.Screening and optimizing the lung cancer related tumor markers from multi-tumor marker protein chip[J].Journal of Chongqing Medical University,2011,36(11):1353-1356. |
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| Authors: | ZHAO Shun-lin HU Wei-dong XU Wen-bo LIU Yue WU Zhou-qing |
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| Institution: | ZHAO Shun-lin1,HU Wei-dong2,XU Wen-bo2,LIU Yue2,WU Zhou-qing2(1.Department of Oncology,the First People's Hospital of Jiangxia District of Wuhan City,2.Department of Oncology,Zhongnan Hospital of Wuhan University,Hubei Key Laboratory of Tumor Biological Behaviors & Hubei Cancer Clinical Study Center) |
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| Abstract: | Objective:To screen and optimize the lung cancer related tumor markers from multi-tumor marker protein chip.Methods:With the multi-tumor marker protein chip,the sera of 311 patients with lung cancer were detected for multi-tumor markers including carcinoembryonic antigen(CEA),alpha fetoprotein(AFP),carbohydrate antigen 199(CA199),cancer antigen 153(CA153),cancer antigen 125(CA125),prostate specific antigen(PSA),free-PSA,and ferritin.Lung cancer related parameters were analyzed by Kappa test and cost-effecti... |
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| Keywords: | tumor markers lung cancer diagnosis |
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