| 舌鳞癌干细胞相关差异表达序列标签的生物信息学分析 |
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| 引用本文： | 邹波,季平,孙守娟,漆小娟. 舌鳞癌干细胞相关差异表达序列标签的生物信息学分析[J]. 重庆医科大学学报, 2011, 36(10): 1233-1236 |
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| 作者姓名： | 邹波 季平 孙守娟 漆小娟 |
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| 作者单位： | 重庆医科大学附属口腔医院颌面外科,重庆,400015 |
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| 基金项目： | 重庆市卫生局科研基金资助项目(编号:2008-2-232) |
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| 摘 要： | 目的:对利用抑制消减杂交技术获得的舌鳞癌干细胞相关表达序列标签(Expressed squence tag,EST)进行电子克隆及序列分析.方法:利用互联网上的公共数据库及生物信息学分析软件对获得的舌鳞癌干细胞相关差异表达序列标签进行核酸序列和蛋白质序列分析,探索克隆差异表达基因的研究方法和策略.结果:通过电子延伸得到...
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| 关 键 词： | 肿瘤干细胞 舌鳞癌 表达序列标签 生物信息学分析 |
Bioinformatics analysis of expressed sequence tag associated with stem cells in tongue squamous carcinoma |
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| ZOU Bo , JI Ping , SUN Shou-juan , QI Xiao-juan. Bioinformatics analysis of expressed sequence tag associated with stem cells in tongue squamous carcinoma[J]. Journal of Chongqing Medical University, 2011, 36(10): 1233-1236 |
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| Authors: | ZOU Bo JI Ping SUN Shou-juan QI Xiao-juan |
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| Affiliation: | ZOU Bo,JI Ping,SUN Shou-juan,QI Xiao-juan(Department of Oral and Maxillofacial Surgery,the Affiliated Stomatology Hospital,Chongqing Medical University) |
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| Abstract: | Objective:To analyze the expressed squence tag(EST) associated with stem cells in tongue squamous carcinoma obtained by suppression subtractive hybrization(SSH).Methods:EST was acquired from stem cells in tongue squamous carcinoma by SSH.Bioinformatics analysis of stem cell related genes was done by the bioinformatic database and biosoftwares such as BLAST and ExPasy analyse soft box.Results:A 1 705 bp complete cDNA sequence was obtained by electronic clone.This cDNA sequence was sited in homo sapiens 1q42,... |
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| Keywords: | tumor stem cell tongue squamous carcinoma expressed sequence tag bioinformatics analysis |
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