| 宁夏回、汉族亚甲基四氢叶酸还原酶基因多态性的分布特点及其与原发性高血压的关系 |
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| 引用本文： | 马萍,覃数,刘海燕,徐清斌.宁夏回、汉族亚甲基四氢叶酸还原酶基因多态性的分布特点及其与原发性高血压的关系[J].重庆医科大学学报,2011,36(11):1364-1367. |
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| 作者姓名： | 马萍 覃数 刘海燕 徐清斌 |
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| 作者单位： | 1. 重庆医科大学附属第一医院心内科,重庆,400016
2. 宁夏医科大学总医院心脏中心,银川,750004 |
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| 基金项目： | 宁夏回族自治区自然科学基金资助项目(编号:NZ10134) |
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| 摘 要： | 目的:研究N5,10-亚甲基四氢叶酸还原酶基因(Methylenetetrahydrofolate reductase,MTHFR)C677T多态性在宁夏回、汉族高血压人群中的分布差异及其与原发性高血压(Essential hypertension,EH)之间的关系.方法:收集回、汉族EH患者146例和155例以及回、...
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| 关 键 词： | N5 10-亚甲基四氢叶酸还原酶 多态性 宁夏 民族 高血压 |
A study of gene ploymorphism of N5,10-methylenetetrahydrofolate reductase (MTHFR) between Hui and Han nationalities in Ningxia and the relationship with essential hypertension |
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| MA Ping
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QIN Shu
,
LIU Hai-yan
,
XU Qing-bin.A study of gene ploymorphism of N5,10-methylenetetrahydrofolate reductase (MTHFR) between Hui and Han nationalities in Ningxia and the relationship with essential hypertension[J].Journal of Chongqing Medical University,2011,36(11):1364-1367. |
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| Authors: | MA Ping QIN Shu LIU Hai-yan XU Qing-bin |
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| Institution: | MA Ping1,QIN Shu1,LIU Hai-yan2,XU Qing-bin2(1.Department of Cardiology,the First Affiliated Hospital,Chongqing Medical University,2.Cardiac Center,General Hospital,Ningxia Medical University) |
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| Abstract: | Objective:To comparatively study distributional characteristics of gene ploymorphism of N5,10-methylenetetrahydrofolate reductase(MTHFR) between Hui and Han nationalities in Ningxia and the relationship between the polymorphism and essential hypertension.Methods:The study was performed in 146 Hui patients and 155 Han patients with essential hypertensive(EH) and was performed in 112 Hui peoples and 140 Han peoples with normal tensive(NT).MTHFR gene polymorphism was detected by polymerase chain reaction-restr... |
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| Keywords: | N5 10-methylenetetrahydrofolate reductase(MTHFR) polymorphism Ningxia nationality hypertension |
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