清热消暑饮对风热感冒的炎性细胞因子影响的探讨 |
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引用本文: | 陈发胜,陈浩生,李文玮,余俊文,周茹,肖雪云.清热消暑饮对风热感冒的炎性细胞因子影响的探讨[J].云南中医中药杂志,2014(3):22-24. |
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作者姓名: | 陈发胜 陈浩生 李文玮 余俊文 周茹 肖雪云 |
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作者单位: | 广东省佛山市中医医院,广东佛山528100 |
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基金项目: | 广东省佛山市三水区科技局计划项目(NO:201216C) |
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摘 要: | 目的 探讨清热消暑饮对风热感冒的炎性细胞因子的影响.方法 将81例风热感冒患者随机分为2组,疗程均为1周:①对照组:40例,口服阿昔洛韦片0.1g,Tid;②治疗组:41例,口服清热消暑饮(银花、连翘、夏枯草、板蓝根、白茅根、桔梗等)1剂/d,Tid.观察用药前后患者的炎性细胞因子的改变.结果 治疗后,2组患者的肿瘤坏死因子TNF-α,白介素IL-1和IL-10,CD4+T细胞百分比均比用药前改善,其中用药后治疗组与对照组的TNF-α、IL-1、CD4+T细胞的差异有统计学意义(P<0.05).结论 清热消暑饮能显著改善风热感冒症状,对炎性细胞因子也有显著影响.
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关 键 词: | 清热消暑饮 风热感冒 炎性细胞因子 |
Effect of Heat-Clearing and Detoxicating Decoction on Inflammatory Cytokines of Patients with Wind-heat Cold |
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Institution: | CHEN Fa- sheng, CHEN Hao- sheng, LI Wen-wei, et al. (Traditional Chinese Medicine Hospital of Foshan City, Foshan 528100, Guangdong ) |
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Abstract: | Objective: To observe the effect of Heat -clearing and Detoxicating Decoction on inflammatory cyto- kines of patients with wind - heat cold. Methods : 81 wind - heat cold patients were randomly divided into 2 groups. One week was a course of treatment, dO patients in the control group took acyclovir po 0. lg Tid orally while 41 patients in the treatment group drank Heat -clearing and Detoxicating Decoction one dose daily, Tid. The changes of the inflammatory cytokines of the patients were observed. Resuhs:TNF- a, IL- 1 ,and the percentage of CD4 +T cell of the two groups improved after the treatment. The difference of these three indexes of the TCM group was statistically significant (P 〈 0. 05) when compared with that of the control group. Conclusion: Heat -clearing and Detoxicating Decoction can significantly improve the symptoms of wind - heat cold patients and has certain effect on their inflammatory cytokines |
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Keywords: | Heat - clearing and Detoxicating Decoction wind - heat cold inflammatory cytokines |
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