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Deletion polymorphism in the angiotensin-converting enzyme gene is not associated with hypertension in a Gulf Arab population |
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| Authors: | P. M. Frossard E. N. Obineche Y. I. Elshahat G. G. Lestringant |
| Affiliation: | Department of Pathology, Faculty of Medicine &Health Sciences, Al Ain;Department of Internal Medicine, Faculty of Medicine &Health Sciences, Al Am;Nephrology Unit, Central Hospital, Abu Dhabi;Department of Internal Medicine, Tawam Hospital, Al Ain, UAE |
| Abstract: | We have studied an insertion/deletion dimorphism in the human angiotensin-converting enzyme gene amongst UAE nationals from the Abu Dhabi Emirate. Our findings show lack of association between the I/D allele marker system and clinical diagnosis of essential hypertension, suggesting that variations of the angiotensin-converting enzyme gene do not play a major role in the determination of elevated blood pressure in this Arab population. This agrees with results reported on other ethnic groups. |
| Keywords: | angiotensin converting enzyme gene association study essential hypertension I/D polymorphism-United Arab Emirates |