中药华泰八宝丹抗癌作用的研究

华泰八宝丹是一种纯中药制剂，用不同剂量对移植性肉瘤S-180Ehrlich腹水癌和恶性淋巴瘤腹水型LI的小鼠进行治疗，按体表面积计算给成人剂量的10倍、5倍和2.5倍，灌胃给药，经重复实验结果：肉瘤S-180抑瘤率三剂量分别为46%、61%、70%；小鼠生命延长率；Ehrlich腹水癌小鼠高剂量为40%，恶性淋巴瘤腹水型LI中、高剂量为35%和51%，对照阳性药物抑瘤率或生命延长率在25%-48%之间，以上数据经统计学处理，有显著意义或非常显著意义。说明本药有一定抑瘤作用，在小鼠可耐受的剂量下，剂量增加抑瘤效果增加。

Research on the Anti-tumor Effects of Traditional Chinese Medicine HuaTai-BaBao-Dan

HuaTai-BaBo-Dan(HBBD) is a genuine traditional Chinese medicine.Different dosages of HBBD were administered to mice with transplanted sarcoma S-180,Ehrlich ascitic carcinoma and malignant lymphoma of ascitic type L_I, by perfusing their stomaches in a course treatment. The High-medium-low-dose groups were respectively 10, 5 and 2. 5 times the dosage for the adult human being calculated on the basis of body surface. The results of repeated experiments showed:The tumor-inhibiting rates for sarcoma S-180 were 46%, 61%and 70%in three different dose groups. The life-prolonging rate for the mice with Ehrlich ascitic carcinoma was 40% in the high-dose group; while for the mice with malignant lymphoma LI, the rates were 35% and 51% respectively in the medium -dose and high-dose groups. The tumor-inhibiting rate or life-prolonging rate were between 25%and 48%in the positive control group. Statistic process of the above data showed obvious or very remarkable differences. It has indicated that HBBD can to a certain degree inhibit tumor. Within their endurable dosage, the heavier the dosage, the better the effect of tumor-inbibiting.