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Multiple floppy valves with all cardiac valves prolapsing: Clinical course and treatment |
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| Authors: | Dr Kiyoshi Suzuki Yasuo Murakami Katsuhiko Mori Yoshiho Hatai Shigekazu Mimori Yukihiro Takahashi Toshio Kikuchi Katsuhiko Tatsuno Takeji Matsushita |
| Institution: | (1) Department of Pediatric Cardiology, Sakakibara Heart Institute, 5-4 Yoyogi 2-chome Shibuya-ku, 151 Tokyo, Japan;(2) Department of Cardiac Surgery, Sakakibara Heart Institute, 5-4 Yoyogi 2-chome Shibuya-ku, 151 Tokyo, Japan;(3) Pediatric Department, National Medical Center Hospital, Tokyo, Japan |
| Abstract: | Summary Two cases with prolapse of all four cardiac valves are described and compared with two similar ones previously reported. The severity and progression of regurgitation of each of the valves differed by case, despite having similar echocardiographic findings consistent with the diagnosis of multiple floppy valves. Two of the four patients had their aortic valve replaced because of severe regurgitation: the excised valves revealed myxomatous degeneration. None of the patients had any stigmata of Marfan or Ehlers-Danlos syndrome, except for the presence of hyperextensive joints. There may be an unknown collagen disorder that caused floppiness in all the valves. |
| Keywords: | Multiple floppy valves Pulmonary valve prolapse Floppy valve syndrome Aortic valve replacement Joint hypermobility syndrome |
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